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Product Info Summary
| SKU: | PA1230 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Mouse, Rat |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-Aquaporin 5/AQP5 Antibody
View all Aquaporin-5 Antibodies
SKU/Catalog Number
PA1230
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-Aquaporin 5/AQP5 Antibody catalog # PA1230. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Aquaporin 5/AQP5 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1230)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of mouse AQP5, identical to the related rat sequence.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PA1230 is reactive to AQP5 in Mouse, Rat
Applications
PA1230 is guaranteed for IHC, WB Boster Guarantee
Observed Molecular Weight
62 kDa
Calculated molecular weight
28.292kDa
Background of Aquaporin-5
Aquaporin 5, also known as AQP5, is a water channel protein. The aquaporins (AQPs) are a family of more than 10 homologous water transporting proteins expressed in many mammalian epithelia and endothelia. At least five AQPs are expressed in the eye: AQP0 (MIP) in lens fiber, AQP1 in cornea endothelium, ciliary and lens epithelia and trabecular meshwork, AQP3 in conjunctiva, AQP4 in ciliary epithelium and retinal Müller cells, and AQP5 in corneal and lacrimal gland epithelia. Among the seven human aquaporins cloned to date (AQPs 0-6), genes encoding the four most closely related aquaporins (AQP0, AQP2, AQP5, and AQP6) have been mapped to chromosome band 12q13, suggesting an aquaporin family gene cluster at this locus. Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Reconsitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Rat, Mouse, By Heat
Western blot, 0.1-0.5μg/ml, Rat, Mouse
Validation Images & Assay Conditions
Click image to see more details
Anti-Aquaporin 5 antibody, PA1230, Western blotting
Working concentration: 0.5μg/ml
Lane 1: Rat Lung Tissue Lysate
Lane 2: Rat Testis Tissue Lysate
Click image to see more details
Anti-Aquaporin 5 antibody, PA1230, IHC(P)
IHC(P): Rat Lung Tissue Lysate
Working concentration: 1μg/ml
Protein Target Info & Infographic
Gene/Protein Information For AQP5 (Source: Uniprot.org, NCBI)
Gene Name
AQP5
Full Name
Aquaporin-5
Weight
28.292kDa
Superfamily
MIP/aquaporin (TC 1.A.8) family
Alternative Names
AQP-5; aquaporin 5; aquaporin-5 AQP5 AQP-5, PPKB aquaporin 5 aquaporin-5
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on AQP5, check out the AQP5 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for AQP5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Aquaporin 5/AQP5 Antibody (PA1230)
Hello CJ!
PA1230 has been cited in 5 publications:
*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.
Expression of AQP1, AQP3, AQP4 and AQP5 in upper respiratory tract of buffaloes during different seasons
Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung
Seasonal effect in expression of AQP1, AQP3 and AQP5 in skin of Murrah buffaloes
Hyperosmotic stress induces cisplatin sensitivity in ovarian cancer cells by stimulating aquaporin-5 expression
Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung
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Customer Reviews
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